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Joshua Silva, MD Nov 7, 2025 13 min read Updated: Apr 17 Medically authored by Joshua Silva, MD | Evidence-Based Weight Loss at Potere Health MD As GLP-1 and GLP-1/GIP medications such as semaglutide (Wegovy, Ozempic) and tirzepatide (Zepbound, Mounjaro) continue to transform medical weight management, one question comes up repeatedly: Do these medications cause muscle lossor even muscle wasting

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For instance, administration of sodium lactate was shown to significantly enhance cardiac performance in patients with acute heart failure, suggesting that the timing and context of lactate modulation are critical and that boosting lactate levels can be beneficial in certain clinical scenarios [139]