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To increase activity, we transitioned to PACE using a more stringent circuit, replacing the T7 RNAP promoter with the weaker T3 RNAP promoter 50 and adjusting RBS strength in front of gIII to reduce transcriptional activation following RNAP liberation (Extended Data Fig

But Roe also said it was a risk for the president to tie himself too closely to top Republicans before the general election, calling it kryptonite to November voters. Trump, who won the White House on a promise to lower the cost of living, also has seen his approval ratings sag, meaning kitchen table issues could be a liability for Republicans trying to hold control of Congress in the Nov

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While these medications offer significant metabolic benefits, questions about their impact on kidney health are common among patients and clinicians

What it captures An MEA is a culture dish embedded with dozens to thousands of microscopic electrodes that can: record extracellular electrical activity from many neurons at once stimulate the network electrically (in some setups) It does not pierce neurons It listens from the outside Analogy- Think of it as a stethoscope for neural networks, not for single neurons