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However, several products do allow limited room temperature storage before first use according to their FDA labels: Wegovy (semaglutide): Up to 28 days at or below 86F (30C) before use Trulicity (dulaglutide): Up to 14 days at or below 86F (30C) before use Mounjaro and Zepbound (tirzepatide): Up to 21 days at or below 86F (30C) before use Bydureon BCise (exenatide extended-release): Up to 4 weeks at or below 77F (25C) before use When storing unopened GLP-1 medications, patients should keep them in their original carton to protect them from light exposure, which can also degrade the active ingredient

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Am J Physiol Renal Physiol (2008) 294(2):F41422

It frames GLP-1 medications as potentially appropriate for people with type 2 diabetes, elevated cardiovascular risk, or obesity at a BMI of 30 or above, while insisting that a provider assessment comes before anyone begins

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