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In clinical studies, people who were prescribed Wegovy lost around 15% of their body weight on average over 68 weeks (slightly over 16 months), compared to only 2-3% in people who didnt take it

This mechanism is the same pathway targeted by phosphodiesterase type 5 (PDE5) inhibitors such as sildenafil (Viagra), which work by preventing the breakdown of cGMP

A bioequivalence study of two formulations of oral semaglutide in healthy participants