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9 Mechanisms of nanomedicine regulating immune cells The physicochemical properties of drug-loaded nanomaterials along with the drugs they carry collectively determine their regulation of immune cells, the mechanisms may involve indirect regulation of immune cells (such as inducing tumor cells to undergo ICD, ferroptosis, or pyroptosis, and targeting tumor-derived exosomes) and direct regulation of immune cells (through activation of the cGAS-STING, NF-Kb, and mTOR pathways, as well as inhibition of SHP2, CD73, or glutaminase)

Trimethylamine N-oxide alleviates the severe aggregation and ER stress caused by G98R alphaA-crystallin

Whole-picture care: We do not look at B12 in isolation

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