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We also observed significant correlation between the PANSS general score ( P =0.035) and total GSH level within the BP patient population
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The placebo group had either an increase or no change in oxidative stress, as shown by a significant increase in MDA in RBCs ( Figure 4E ) or no change in MDA in plasma ( Figure 4C ) or PBMCs ( Figure 4D )
Protein and lipid pellets were discarded, while 10 L injections of supernatants were analyzed via a Vanquish UHPLC system (Thermo Fisher Scientific) coupled to a Q Exactive mass spectrometer (Thermo Fisher Scientific) utilizing an untargeted acquisition as previously reported 18
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