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Do not wait for a scheduled appointment or attempt to manage severe symptoms at home

In Phase II, we observed a non-significant trend toward higher plasma L-carnitine concentrations in the pomegranate extract condition compared to placebo across the 48-h pharmacokinetic period (Supplementary Figure 8A)

doi: 10.1038/s41392-024-01769-5, 154 ZhouZ

Common side effects include: Nausea and vomiting Diarrhoea or constipation Reduced appetite Abdominal discomfort or bloating Injection site reactions (redness, itching, or mild swelling) These effects can often be managed by eating smaller, lower-fat meals, avoiding lying down immediately after eating, staying well hydrated, and adhering to the gradual dose-escalation schedule

13 These findings suggest that supporting gut health with probiotics, prebiotics, and fiber may indirectly enhance GLP-1 activity and overall metabolic function