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Patients may change the day of weekly administration if necessary, provided that the time between two doses is at least 3 days (72 hours)

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Exercise alternatives, location changes, and clear movement context help the plan stay practical instead of becoming a rigid checklist

Certain conditions seem to be associated with the development or worsening of restless legs syndrome, including: Iron deficiency (with or without anemia) Kidney failure Diabetes Parkinsons disease Damage to the nerves in the hands or feet (peripheral neuropathy) Rheumatoid arthritis Pregnancy Medications that may aggravate RLS symptoms include: Antinausea drugs, such as prochlorperazine (Compazine) or metoclopramide Antipsychotic drugs, such as haloperidol (Haldol) or phenothiazine derivatives Some cold and allergy medications that contain older antihistamines like diphenhydramine In some cases, the use of antidepressants How Is Restless Legs Syndrome Diagnosed