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A 2017 randomised controlled trial published in Clinical, Cosmetic and Investigational Dermatology found that 500mg oral glutathione twice daily for 12 weeks produced a mean melanin index reduction of 17.6% vs 2.1% placebo, measured by chromameter

PANC-1 cells stably transfected with shGSTM3 and shNC were injected into nude mice subcutaneously

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