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Completely agree with your framing: menopause is a metabolic inflection point, and outcomes are best when we treat the whole system, not one pathway in isolation
Clinical trials for HS treatment: next-generation antibodies and intracellular signaling inhibitors Beyond currently approved biologics used as standard therapies in HS as well as conventional and surgical treatments, a growing number of clinical trials are evaluating novel therapeutic strategies, based on the refined immune-pathogenesis understanding and the urgent need to better manage patients with refractory disease and extensive structural damages
Cortisol stimulates adipogenesis in visceral depots, wastes muscle in extremities, and pushes free fatty acids into circulation (PMC7827500)
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