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Standard therapeutic dosages usually fall in this range, with 1000 mcg often suggested

Breast milk concentration increased from an average of 55 pmol/l to about 1,000 pmol/l

This may theoretically produce additive effects on weight loss and metabolic parameters, though this interaction has not been extensively studied in controlled trials

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To get a truer picture, they often check for high levels of methylmalonic acid (MMA) and homocysteine