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New GLP-1 users who have not established a supplement routine yet are good candidates for Replenza

Written by: Leanne Edermaniger, M.Sc

Stephen Sinatra

Maintenance and Long-Term Use: STEP-4 Trial: Participants who stopped semaglutide regained most weight Those who continued maintained loss and continued losing Suggests long-term treatment necessary for maintenance Most experts recommend: Treating obesity as chronic disease Long-term or indefinite medication use Transitioning to maintenance dose (not stopping) Combining with lifestyle changes for best results Understanding the complete comparison between semaglutide and tirzepatide helps determine which medication best fits your goals

It binds to the glucagon-like peptide 1 (GLP-1) hormone and potentiates the synthesis and secretion of insulin from pancreatic -cells in a glucose-induced manner (Underwood et al., 2009)