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Its not a medication in the strict sense, but its one of the few over the counter options with actual PCOS-specific data behind it
The first batch of Dermalogicas new Dynamic Skin Sculptor, a tightening body serum to combat laxity from rapid weight loss, sold out on the brands website within a week of launch
Semaglutide causes significant appetite suppression, which leads to reduced caloric intake, which can deplete NAD+ levels, which reduces cellular energy, which contributes to GLP-1 fatigue
PMID: 37276988
Thats why high-fat meals or large portions can worsen nausea, so avoid these, eat slowly, and stop once youre full
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