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Monitor Kidney Function Regular lab tests (e } Summary of Clinical Evidence Meta-analyses and observational trials have reported: A 1622% relative reduction in kidney-related outcomes in some GLP-1 studies compared to placebo, observed in controlled clinical settings Lower levels of albuminuria and slower eGFR decline among patients treated with GLP-1 medications in certain trials Observed cardiovascular effects in patients with both diabetes and CKD, though these outcomes were studied using FDA-approved products under provider supervision Final Thoughts GLP-1 medications like semaglutide are FDA-approved for blood sugar and weight management in type 2 diabetes