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As the authentic GnRH decapeptide sequence without structural modification, it serves as the gold-standard tool compound for GnRH receptor pharmacology studies and is the reference against which GnRH analogs (leuprolide, buserelin, degarelix) are benchmarked
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Similarly, TB-500 has undergone extensive safety evaluation including human research trials showing safety at intravenous doses up to 1,260 mg equivalent, with no dose-limiting toxicities or serious adverse events attributable to the peptide in carefully controlled studies
213 ZhengB.WangC.HeL.XuX.QuJ.HuJ.et al (2013)
[4] The material supplied here is an unapproved research chemical for laboratory use only and is not that medicine
