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Collectively, the data from 20 healthy nonobese subjects indicated that elevated colonic propionate production diminished striatal blood oxygen level-dependent signals, especially in reaction to high-energy foods, indicating that propionate mitigates reward-driven eating behavior through striatal pathways, irrespective of alterations in plasma PYY, GLP-1, glucose, or insulin levels

In Part X, when we dig into the specific GLP-1 RA peptides, keep in mind how the bodys innate GLP-1 release begins as a response to both the foods we eat and the state of our microbiome

BMJ, 388, q2440

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