Toxicol Lett
Repeated injections in one location can cause lipohypertrophy (thickened fatty tissue) or lipodystrophy, which affects peptide absorption and creates visible bumps
Schneider SA, Dusek P, Hardy J, Westenberger A, Jankovic J, Bhatia KP
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Antibodies specific for p70S6 kinase, phospho-p70S6 kinase (Thr 389), S6 ribosomal protein, phospho-S6 ribosomal protein (Ser 235/236), eIF2, phospho-eIF2 (Ser 51), PERK, Bip and horseradish peroxidase (HRP)-linked secondary antibodies were from Cell Signaling Technology (Danvers, MA, USA)