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5-Days-On, 2-Days-Off Protocol Monday-Friday : Daily injections Saturday-Sunday : Rest days Benefits : Prevents receptor desensitization, maintains natural pulsatile patterns, reduces cost This cycling approach mimics natural growth hormone patterns while preventing tolerance development commonly seen with continuous daily use

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doi: 10.1210/jendso/bvab048.013 Formichi C, Fignani D, Nigi L, et al