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The most useful way to think about injection site reactions is to separate short-lived irritation from signs of infection, allergy, or a pattern that keeps coming back in the same spot
Fatigue rates are similar across GLP-1 agonists (semaglutide, tirzepatide, dulaglutide), though individual response varies by genetics and dose
The short version: if you're only doing bodyweight or flexibility work while on a GLP-1, you're losing muscle you can't afford to lose
GHK-Cu, while not primarily "cleared" through hepatic metabolism in the traditional sense, introduces exogenous copper that is entirely dependent on hepatic processing and biliary excretion
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