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SGLT2 Inhibitors and Cardioprotection: A Matter of Debate and Multiple Hypotheses
Fibroblasts are like construction workers: They move into damage sites, building new tissue scaffolding
doi: 10.1155/2012/745483 5 Centers for Disease Control and Preventation (2016)
performed a cross-trial analysis using data from clinical trials of GLP-1RAs (ELIXA, LEADER, SUSTAIN-6, EXSCEL, HARMONY, REWIND, PIONEER-6 [59], and AMPLITUDE-O), SGLT2is (CANVAS and CREDENCE), and finerenone (FIDELIO-DKD and FIGARO-DKD) to estimate the effects of the triple combination therapy of GLP-1RA, SGLT2i, and finerenone using the actuarial method [60]
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