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Activating both pathways together produces a more pronounced effect on appetite suppression, fat loss, and metabolic efficiency than either pathway alone which is why clinical trial data consistently shows tirzepatide producing greater average weight loss than single-receptor GLP-1 medications
Effects on the Vagus Nerve Tirzepatide works partly through the vagus nerve , which controls many automatic functions in the body like heart rate and digestion
Over the past two years, one medication has clearly changed the trajectory of medical weight loss more than anything else Ive seen in my career: tirzepatide
doi: 10.5314/wjd.v9.i1.1 534 BrodmannTEndoAGueimondeMVinderolaGKneifelWde VosWMet al
Biomaterials 287:121616
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