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Flare frequency decreased in 60%, NRS-Pain in 52%, NRS-Suppuration in 53% and DLQI in 50% of patients
A network meta-analysis examining 105 randomized controlled trials with over 219,000 participants found no significant association between GLP-1 receptor agonists and increased infection risk, including urinary tract infections
A mean increase in HR of 1.86 beats/min was reported in a meta-analysis including available data from randomized controlled trials testing GLP-1 agonists against placebo in patients with T2D [53]
Others find the strict timing requirements of oral GLP-1s harder to maintain than a weekly injection they can schedule around their life
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