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Before starting, doctors check for conditions like personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 (MEN 2), as semaglutide should not be used in these cases
Structural analogy to tirzepatide suggests fewer class-effect signals than semaglutide (3/6 vs 5/6 FAERS signals
The A Study of Tirzepatide on the Reduction on Morbidity and Mortality in Adults with Obesity (SURMOUNT-MMO) trial assesses tirzepatide's impact on mortality and cardiovascular events in overweight or obese individuals
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