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Brachycephalic breeds (eg, pugs, Boston terriers, English and French bulldogs) and Shar-peis have excessive skin folds, especially on the face, that can trap moisture and predispose these breeds to fungal or bacterial skin infections
Hydration focus : Aim for 64-80 ounces of water daily for most adults (unless fluid-restricted), consumed between meals rather than with food to avoid premature fullness
Wang, C., Sun, S., Jiao, J., Yu, X
the GHK-Cu guide covers that background
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