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This is not a failure of science its how science works

Bundy DG, Byerley JS, Liles A, et al

Does the GIP receptor agonism in retatrutide affect the heart

Effect of the GLP-1 receptor agonist semaglutide on metabolic disturbances in clozapine-treated or olanzapine-treated patients with a schizophrenia spectrum disorder: study protocol of a placebo-controlled, randomised clinical trial (SemaPsychiatry)