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Rapid Drop in Blood Sugar or Caloric Intake Retatrutide can sharply reduce appetite, leading to: Low caloric intake Low blood sugar (even in non-diabetics) Electrolyte imbalance These metabolic changes can trigger symptoms very similar to anxiety: Racing heart Shakiness Restlessness A sense of being on edge 2

Grunvald and New York internist and longevity expert Amanda Kahn, MD

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This finding suggests that the peptide may have an impact on the course of depression

However, the evidence for meaningful clinical benefit in elderly populations remains preliminary, and the risk-benefit calculation must account for potential effects on glucose metabolism and cancer risk