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The melanocortin receptor agonist Setmelanotide has shown efficacy in these conditions, being a selective agonist of the MC4R it mimics the action of the alpha MSH and represents a hormonal replacement therapy
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[2] In other words, the pituitary continues to fire in bursts even when the GHRH signal is sustained, because somatostatin continues to impose its rhythm on top of that signal
Further studies also show it can lower your blood pressure and cholesterol levels
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