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In patients with HFpEF and obesity, both semaglutide (STEP-HFpEF) and tirzepatide (SUMMIT) significantly reduced cardiovascular death and worsening heart failure events, with concomitant improvements in quality of life and functional capacity [3,47]
The larger volume reduces relative measurement error
doi:10.1007/s11095-012-0917-z 179
Starting with lower doses and gradual escalation helps minimize side effects
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