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It doesnt discriminate against different types of fat and can affect facial fat, which is necessary for structural support and a youthful look, says California-based facial plastic surgeon Steven Curti, MD

First, the patients pre-existing obesity, with a BMI of 28.7, may have predisposed him to a heightened metabolic and inflammatory state, amplifying the drugs effects on the liver

For most patients, acid reflux occurs during the first one to three weeks after starting retatrutide or after a dose increase

The result was a population of nearly 18,400 who were evenly split between the two drugs

Evaluating Tirzepatide vs Semaglutide for Weight Loss: What About Side Effects