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A 2025 meta-analysis of 33 placebo-controlled randomized trials involving nearly 6,000 participants found that GLP-1RAs modestly (but significantly) reduced LDL cholesterol and total cholesterol, and interestingly, weight change did not influence these lipid outcomes
Due to the risk of thyroid cancer with Saxenda, the medication has a boxed warning about this side effect
In mice, GDF-15 increases satiety and reduces food intake through actions in the central nervous system [99]
The coming years could totally transform metabolic medicine.
In lung cancer, Sirichanchuen et al
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