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Both animal and human studies have shown insulin resistance alters dopaminergic signalling in the nucleus accumbens [14, 15] and comorbid metabolic factors are shown to exacerbate motivational deficits in major depressive disorder [16]

In Vitro Antifungal Activity of Manogepix and Other Antifungal Agents against South African Candida auris Isolates from Bloodstream Infections