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While Retatrutide has not shown increased depression or suicidal ideation in trials, any weight loss medication should be used cautiously in individuals with active severe depression or history of eating disorders
Conversely, a study by Gasbjerg et al
16 ), have also been explored as potential cancer treatments
Abbreviations LC: L-carnitine TC: Total carnitine TMAO: Trimethylamine-N-oxide CHO: Carbohydrates IGF-1: Insulin-like growth factor-1 PI3K: Phosphoinositide-3-kinase Akt: Protein kinase B mTOR: Mammalian target of rapamycin S6K: S6 kinase 4E-BP: 4E-binding protein FoxO: Forkhead box O MuRF-1: Muscle-specific RING finger-1 atrogin-1: Muscle atrophy F-box mRNA: Messenger RNA BMI: Body mass index ROS: Reactive oxygen species References Bremer J
prompt clinical review is warranted if these occur
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