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Moreover, considering that carnitine metabolism produces TMAO, which has been recently recognized as a novel risk factor for cardiovascular diseases, the use of uncontrolled amounts of carnitine as dietary supplements must be carefully reviewed. "Since carnitine is often used by athletes with no clear understanding of its effects and risks, it becomes critical to provide information about the characteristics of this compound and its probable harmful effects on health," the researchers said

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Nevertheless, there have been no investigations assessing IAA concentrations in brain tissue