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Biochemistry of the pentose phosphate pathway (PPP) Glucose-6-phoshphate dehydrogenase (G6PD) is the enzyme for the first step of the pentose phosphate pathway (also called hexose monophosphate shunt or phosphogluconate pathway ) G6PD reduces NADP to NADPH while oxidizing glucose-6-phosphate, which is the rate-limiting step of the pathway The pentose phosphate pathwayis a metabolic pathway which uses glucose-6-phosphate to produce: NADPH (most important) Phosphorylated sugars F6P and GAP

Glucose-6-phosphate dehydrogenase deficiency and diabetes mellitus

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