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Nevertheless, ADA 2023 suggests that metformin's benefits on MACE remain potential and dubious [9], indicating that for patients with high risk of MACE, metformin combined with SGLT-2i or GLP-1 RAs with proven cardiovascular benefits may still contribute to the decrease of MACE risk

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unlike generic medications, which are FDA-approved drugs without brand names that are introduced into markets after patents expire, compounded drugs are intended as substitutes provided for specific reasons (like drug shortages) and are not subject to the same approval processes

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Wang T, Arifoglu P, Ronai Z and Tew KD

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However, if they stop slowly, and have expanded their awareness and understanding of healthy lifestyle behaviors and eating habits, their hunger and satiety will be more manageable, making it easier for them to maintain a healthy weight. Everyones journey with GLP-1 medications is different

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