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The substitution that does the real work is D-Ala2, which blocks cleavage by dipeptidyl peptidase-4, the protease that degrades native GHRH within minutes
J.SharmaA.BukshS.TateM.de HaanJ
P.AlbengresE.TestaB.CarruptP.et al (1996)
L'estere grasso acil-carnitina formatosi si diffonde poi attraverso lo spazio intermembrana dei mitocondri ed entra nella matrice mediante trasporto passivo attraverso il cotrasportatore acil-carnitina / carnitina che si trova nella membrana mitocondriale interna
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