(MOV 27950 kb) Three distinct microglial morphologies generated in response to compression injury (download MOV A representative time lapse showing the three distinct microglial morphologies was captured in a CX3CR1 mouse beginning 5 min following compression injury
Dosing After Reconstitution: Volume Reference Table With a 2 mg vial reconstituted in 1 mL bacteriostatic water (2,000 mcg/mL concentration): With a 5 mg vial reconstituted in 2.5 mL bacteriostatic water (2,000 mcg/mL concentration): At the standard no-DAC protocol of 100 mcg before bed, a single 5 mg vial provides 50 doses: nearly two months of daily injections
Three components One defined tripeptide Glutathione is formed from glutamic acid, cysteine and glycine joined together as one tripeptide compound
Published human studies (Dhillo et al., JCEM, 2005) used IV bolus doses and observed rapid hormonal responses
i 2+ K : Beta-2 receptor stimulation has been shown to stimulate calcium-activated potassium (KCa) channels in airway smooth muscle by both PKA-induced phosphorylation, and membrane-delimited Gs pathways (Kume et al, 1994)