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Hepatic cholesterol metabolism involves multiple parts, including cholesterol uptake, synthesis, biotransformation, and efflux

Original unopened vials are described as remaining refrigerated until their expiration date, typically 24 to 36 months out, whereas an in-use vial at room temperature is the common active-treatment scenario with a much shorter window

Two 131-patient cohorts with balanced baseline characteristics were formed by propensity score matching

More specifically, the 200mg group saw a 2.4% reduction, while the 400mg and 800mg groups experienced reductions of 1.9% and 1.7%, respectively