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Tebay LE, Robertson H, Durant ST, Vitale SR, Penning TM, Dinkova-Kostova AT, et al
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Patients with a history of hepatic disease require heightened surveillance and cautious dose adjustment
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Trajectoire type : Poids dpart : 92 kg Phase 1 (12 mois Wegovy) : -16 kg 76 kg (17% perte) Arrt traitement (contrainte budgtaire) Phase 2 (12 mois post-arrt) : +10 kg 86 kg Pattern observ (donnes STEP 4 bras placebo) : Mois 1-3 post-arrt : Poids stable Mois 4-6 : Retour apptit progressif Mois 7-12 : Regain acclr (fringales, portions augmentes) Regain mdian : 62,5% du poids perdu (10 kg sur 16 kg) Leon STEP 4 : Wegovy = traitement chronique
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