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GLP: glucagon-like peptide HF: hydrogen fluoride HHMI: Howard Hughes Medical Institute MGH: Massachusetts General Hospital NIH: National Institutes of Health PI: Principal Investigator SPPS: solid-phase peptide synthesis USPTO: United States Patent and Trade Office 1 E.g., Jimmy Kimmels opening monologue in 2023 from the 95 th annual Academy Awards ceremonies, ( at 2:27