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STEP-1 followed 1,961 adults on weekly semaglutide for 68 weeks, and SURMOUNT-1 followed 2,539 adults on tirzepatide for 72 weeks

But when the discs start deteriorating, pain sets in, signaled by neurons in the area

For those who struggle with painful straining, generic Colace is a gentle addition

Here is how GLP-1 options compare, according to clinical trials: Daily oral semaglutide (Wegovy): Average weight loss of 13.6 percent of body weight after about 15 months of treatment, compared with 2.2 percent in a placebo group Average weight loss of 11.2 percent of body weight after 72 weeks of treatment, compared with 2.1 percent in the placebo group

Compare that to the larger, long-term studies that found no significant connection between GLP-1 meds and vision problems