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The amount of cyanide released from B12 supplementation is minuscule compared to dietary exposure from foods like almonds, cassava, and cruciferous vegetables
Since B12 is mainly found in animal products, individuals following vegan or vegetarian diets are at higher risk of deficiency and often need to supplement
The practical sweet spot lands between 300-500mcg daily for most individuals
Obesity and Weight Studies: Published Phase 2 data (NEJM, 2023) showed up to 24.2% mean body weight reduction at 48 weeks
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