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The published Phase 3 trial data conclusively demonstrates CagriSema, the combination of both, produces superior weight loss and metabolic outcomes compared to either peptide used alone, with a safety profile comparable to Semaglutide monotherapy
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GAPDH was used as a loading control ( n = 3).( B ) cAMP levels in coronary effluents were measured at timed intervals during an initial 10-minute perfusion of WT hearts with either 6 nM GLP-1(2836), scrambled(2836) control (Scram), or buffer-only control (Cntl), or with 0.3 nM GLP-1, and were normalized to coronary flow (mL/min/g heart weight)
Diabetes (2018) 67(11):24109
