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This result approximates to the 24-h loss if there is no large body surface area deviation.69 It must be considered that there is high variability among albuminuria measurements, so to confirm the existence of pathological albuminuria, more than one sample is required.10,11 Factors that may influence albuminuria determination independent of kidney damage are exercise, infections, fever, congestive heart failure, menstruation and hyperglycemia or very high blood pressure.12 Two elevated values in three samples obtained at least three months apart are necessary to consider the presence of significant albuminuria

Kahn MG, Callahan TJ, Barnard J, et al

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Efficacy of N-Acetylcysteine in Polycystic Ovary Syndrome: Systematic Review and Meta-Analysis