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Indirect Evidence for A Role of Redox Dysregulation in Als As well as the studies described above, there is also evidence that cellular processes associated with redox homeostasis are dysregulated in ALS (Figure 2)

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The conjugation of glutathione on the previously hydrophobic-toxic substrate results in a soluble compound, which is more readily exocytosed by the cell

Saudi J Biol Sci 20(4):383388