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DERET assay GLP-1R internalization in real-time 26 was measured in CHO-SNAP-GLP-1R cells labeled with Lumi4-Tb and incubated with 24 M fluorescein in HBSS
Some patients also have nausea diarrhea vomiting constipation early on
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Although patients receiving exenatide IR and experiencing longer durations of nausea and vomiting tended to lose more weight, those in the trial group who did not experience the gastrointestinal symptoms (70%) generally lost weight as well (166, 224)
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