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They discovered early that there was a correlation between ATP levels and free carnitine.[2] Jumping ahead 35 years, another team completed a review that showed carnitine has favourable effects in everything from hypertension and diabetic ketoacidosis to cardiac arrhythmias and ischemic-reperfusion injuries.[3] L-carnitine has also been shown to increase energy levels, and may be helpful for people who are struggling with fatigue
Regarding the efficacy of oral lipoic acid supplementation, an initial short-term study in 24 patients with type 2 diabetes mellitus found that the symptoms of peripheral neuropathy improved in those who took 600 mg of lipoic acid three times a day for three weeks compared to those who took a placebo (75)
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