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Due to the pure vitamin C (Ascorbic acid) content, there may be discoloration and changes in odor at high temperatures, so please store in a cool, dark place (or refrigerate) after opening
These oxidative entities have dual effects on nuclear factor (NF)-B signaling, either activating or inhibiting it to produce anti- or pro-oxidative responses 12
Comparing the effects seen here to a model using a melatonin-competent mouse, for example from the CBA strain, would be beneficial for future studies that consider in more detail the phasing of melatonin treatment in vivo
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