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Some reasons patients consider deprescription include: Negative side effects Cost and coverage challenges Difficulty adhering to treatment Reaching their health goals Hitting a weight-loss plateau Preference not to remain on medication long term Without a comprehensive lifestyle and nutrition plan, many patients who stop GLP-1s regain the weight they lost
In clinical trials, people who took semaglutide lost more weight compared to those who took a placebo, which is a pill with no active ingredients
And in one of the studies, 16 of the 45 participants dropped out before the study ended
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