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Description

consistent ~12-15% weight loss at 68 weeks Compound Tirzepatide (Zepbound) Class GIP/GLP-1 dual agonist FDA Status FDA-approved for chronic weight management Evidence Strength Phase 3 RCTs

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Compounding Pharmacies Jump on Shortage Opportunity In 2022, the FDA added Eli Lillys Zepbound and Novo Nordisks Wegovyalong with their sister GLP-1s for diabetes, Mounjaro and Ozempic, respectivelyto its list of drugs in shortage, opening the door for compounding pharmacies to legally produce compounded versions for patients who were not able to source branded products

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Lofton says many doctors will prescribe the anti-diabetic off-label for prediabetes because it is relatively inexpensive

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doi:10.1016/j.bbi.2012.01.006 [3] Bucci I, Giuliani C, Di Dalmazi G, Formoso G, Napolitano G

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Food and Drug Administration (2023)

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